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劉怡旻教授

 


JournalPatent

 

劉怡旻教授      
辦公室:U717    
分   機: 2717    

學歷:
  1. 國立成功大學醫學院,基礎醫學研究所,博士
  2. 中國醫藥學院,藥學系,學士
現職:
大仁科技大學 藥學系 教授

經歷:

  1. 大仁科技大學 藥學系 副教授,94年1月~97年6月
  2. 大仁技術學院 藥學系 助理教授,90年8月~93年12月

Email:

專長:

1. 教授科目:藥理學、藥物治療學、中藥藥理
2. 研究主題
a.我們的研究目的是希望能藉由胰島素抗性動物模式的建立探討中草藥及其純化物或化學合成衍生物對葡萄糖代謝有關的影響,進一步釐清其在整個身體系統內抗代謝性症候群及其併發症的效力;並且針對一些具降血糖、調節血脂或是抑制脂肪蓄積活性的中藥及其純化物或化學合成衍生物進行作用機轉的解明。
b.我們亦針對傳統中藥方劑進行改善糖尿病腎臟病變之藥效及可能引至毒性進行評估,並確定中藥服用及中西藥合併其療效及可能引致之副作用,藉以釐清中西藥併用於改善糖尿病腎病變的藥效及安全性的參考。
 

 

 Journal Papers

  1. Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM (2013). Reduction of lipid accumulation in white adipose tissues by Cassia tora (Leguminosae) seed extract is associated with AMPK activation. Food Chemistry, 136(2),1086-1094. 本人為通訊作者.
  2. Tzeng TF, Liu IM (2013). 6-Gingerol prevents adipogenesis and the accumulation of cytoplasmic lipid droplets in 3T3-L1 cells. Phytomedicine, 20(6), 481-487. 本人為通訊作者.
  3. Chen WC, Liou SS, Tzeng TF, Lee SL, Liu IM (2012). Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats. BMC Complementary and Alternative Medicine, 12(1), 226. 本人為通訊作者.
  4. Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM (2012). Cassia tora (Leguminosae) seed extract alleviates high-fat diet-induced nonalcoholic fatty liver . Food and Chemical Toxicology, 51C, 194-201. 本人為通訊作者.
  5. Chang CJ, Tzeng TF, Liou SS, Chang YS, Liu IM (2012). Absence of genotoxic and mutagenic effects of Zingiber zerumbet (L.) Smith (Zingiberaceae) extract. Evidence-Based Complementary and Alternative Medicine , doi:10.1155/2012/406296. 本人為通訊作者.
  6. Lai MC, Liu IM, Liou SS, Chang YS (2012). Radix Aconiti kusnezoffii Exhibits an Antinociceptive Activity Involvement at Central and Peripheral Nervous System . Journal of Food and Drug Analysis, 20(2):501-509. 本人為通訊作者.
  7. Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM (2012). Emodin protects against high-fat diet-induced obesity via regulation of AMP-activated protein kinase pathways in white adipose tissue. Planta Medica, 8(10):943-950. 本人為通訊作者.
  8. Chang CJ, Tzeng TF, Liou SS, Chang YS, Liu IM (2012). Regulation of lipid disorders by ethanol extracts from Zingiber zerumbet in high-fat dietinduced rats. Food Chemistry, 132(1): 460-467. 本人為通訊作者.
  9. Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM (2012). Emodin, a naturally occurring anthraquinone derivative, ameliorates dyslipidemia by activating AMP-activated protein kinase in high-fat-diet-fed rats. Evidence-Based Complementary and Alternative Medicine, doi:10.1155/2012/781812. 本人為通訊作者.
  10. Chang CJ, Tzeng TF, Chang YS, Liu IM (2012). Beneficial impact of Zingiber Zerumbet on insulin sensitivity in fructose-fed rats. Planta Medica, 78(4):317-25. 本人為通訊作者.
  11. Chang CJ, Tzeng TF, Liou SS, Chang YS, Liu IM (2012). Acute and 28-day subchronic oral toxicity of an ethanol extract of Zingiber zerumbet (L.) Smith in rodents. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012/608284 本人為通訊作者.
  12. Liu IM, Tzeng TF, Liou SS, Chang CJ (2012). Regulation of obesity and lipid disorders by extracts from Angelica acutiloba root in high-fat diet-induced obese rats. Phytotherapty Research, 26(2):223-230. 本人為通訊作者.
  13. Liu IM, Tzeng TF, Liou SS, Chang CJ (2012). Beneficial effect of traditional Chinese medicinal formula danggui-shaoyao-san on advanced glycation end-product-mediated renal injury in streptozotocin-diabetic rats. Evidence-Based Complementary and Alternative Medicine , doi:10.1155/2012/140103. 本人為通訊作者.
  14. Tzeng TF, Lu HJ, Liou SS, Chang CJ, Liu IM (2012). Vinegar-baked Radix Bupleuri regulates lipid disorders via a pathway dependent on peroxisome roliferator-activated receptor-α in high-fat diet-induced obese rats. Evidence-Based Complementary and Alternative Medicine. 本人為通訊作者.
  15. Chang CJ, Tzeng TF, Liou SS, Chang YS, Liu IM (2011). Kaempferol regulates the lipid-profile in high-fat-diet fed rats through an increase in hepatic PPARα levels. Planta Medica, 77(17):1876-82. 本人為通訊作者.
  16. Hsu JH, Wu YC, Liu IM, Cheng JT (2011). Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats. Journal of Ethnopharmacology, 112(3):577-584.
  17. Lai MC, Liu IM, Liou SS, Chang YS (2011). Mesaconitine plays the major role in the antinociceptive and anti-inflammatory activities of radix Aconiti Carmichaeli (Chuan Wu). Journal of Food and Drug Analysis, 19(3):362-8.
  18. Liu IM, Tzeng TF, Liou SS, Chang CJ (2011). Angelica acutiloba root alleviates advanced glycation end-product-mediated renal injury in streptozotocin-diabetic rats. Journal of Food Science, 76(7): H165-74. 本人為第一作者、通訊作者.
  19. Liu IM, Tzeng TF, Liou SS (2011). A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis, Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats. Evidence-Based Complementary and Alternative Medicine, doi:10.1093/ecam/nep004. 本人為通訊作者.
  20. Liu IM, Tzeng TF, Liou SS, Chang CJ (2011). Angelica acutiloba root attenuates insulin resistance induced by high-fructose diet in rats. Phytotherapty Research, 25(9):1283-1293. 本人為第一作者、通訊作者.
  21. Chan P, Liu IM, Li YX, Yu WJ, Cheng JT (2011). Antihypertension induced by tanshinone IIA isolated from the roots of Salvia Miltiorrhiza. Evidence-Based Complementary and Alternative Medicine, 2011:392627. doi: 10.1093/ecam/nep056.
  22. Tzeng TF, Liou SS, Liu IM (2011). Myricetin ameliorates defective postreceptor insulin signaling via B-endorphin signaling in the skeletal muscles of fructose-fed rats. Evidence-Based Complementary and Alternative Medicine, doi:10.1093/ecam/neq017. 本人為通訊作者.
  23. Liu IM, Cheng JT (2011). Mediation of Endogenous β-Endorphin in the Plasma Glucose-Lowering Action of Herbal Products Observed in Type 1-Like Diabetic Rats . Evidence-Based Complementary and Alternative Medicine, 2011:987876. doi: 10.1093/ecam/nen078. 本人為第一作者.
 

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Patent

  1. 劉怡旻;張家茹;劉崇喜,“A ginger extract for inhibiting the fat-storage funvtion of adipocytes”, 美國發明專利,已核准證書字號:US 8,501,249 B2
  2. 劉崇喜;劉怡旻;張家茹;唐偉智,“Herbal preparation for anemia and a manufacture method thereof”, 美國發明專利,已核准證書字號:US 8,420,136 B2
  3. 劉崇喜;劉怡旻;陳威丞,『牛樟芝圓粒結構』,大陸實用新型專利,已核准證書字號:2628188,2012.6.28~2022.06.27。
  4. 劉崇喜;劉怡旻;李瑞瑜,『從山藥塊根外皮萃取抗氧化物質之製備方法』,中華民國發明專利,已核准證書字號:I379687,2012.12.21 ~ 2029.9.8。
  5. 劉崇喜;劉怡旻;陳威丞,『封閉式牛樟芝物流管控裝置』,中華民國新型專利,已核准證書字號:M443892,2012.12.21~2022.6.25。
  6. 劉崇喜;劉怡旻;黃郁婷,『抑制腫瘤的藥用真菌藥錠結構』,大陸實用新型專利,已核准證書字號:2544155,2011.12.9~2021.12.8。
  7. 劉崇喜;劉怡旻;陳威丞,『具有光照單元的牛樟芝培養箱』,大陸實用新型專利,已核准證書字號:2449463,2012.3.1~2022.2.31。
  8. 劉崇喜;劉怡旻;陳威丞,『牛樟芝物流管控裝置』,大陸實用新型專利,已核准證書字號:2448387,2012.1.20~2022.1.19。
  9. 劉崇喜;劉怡旻;陳威丞,『具有光照單元的牛樟芝培養箱』,中華民國新型專利,已核准證書字號:M433086,2012.7.11~2022.2.22。
  10. 劉崇喜;劉怡旻;陳威丞,『牛樟芝培養箱』,大陸實用新型專利,已核准證書字號:2239177,2011.9.29~2021.9.28。
  11. 劉崇喜;劉怡旻;陳威丞,『牛樟芝物流管控裝置』,中華民國新型專利,已核准證書字號:M429146,2012.5.11~2022.1.12。
  12. 劉怡旻;劉崇喜;張家茹,『薄荷抗氧化物質之恆溫萃取法』,中華民國發明專利,已核准證書字號:I361097,2012.4.1~2029.8.30。
  13. 劉崇喜;劉怡旻;黃郁婷,『具抑制腫瘤之藥用真菌藥錠結構』,中華民國新型專利,已核准證書字號:M425668,2012.4.1~2021.11.28。
  14. 劉崇喜;劉怡旻;陳威丞,『牛樟芝培養箱』,中華民國新型專利,已核准證書字號:M421698,2012.2.1~2021.9.22。
  15. 王伯綸;劉崇喜,劉怡旻;張家茹,『微膠囊』,大陸實用新型專利,已核准證書字號:1925283,2011.1.26~2021.1.25。
  16. 劉崇喜;劉怡旻;黃郁婷;張家茹,『四物滴丸』,中華民國新型專利,已核准證書字號:M408367,2011.8.1~2021.1.24。
  17. 劉崇喜;劉怡旻;黃郁婷;張家茹,『四物滴丸』,大陸實用新型專利,已核准證書字號:2300506,2011.7.15~2021.7.14。
  18. 王伯綸;劉崇喜,劉怡旻;張家茹,『當歸微膠囊』,中華民國新型專利,已核准證書字號:M404712,2011.6.1~2020.12.16。
  19. 劉崇喜;劉怡旻,『中藥當歸之定量定溫及定時炮製法』,中華民國發明專利,已核准證書字號:I339123,2011.3.21~2027.9.6。

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