蔡逸宏助理教授

蔡逸宏助理教授

蔡逸宏 助理教授

辦公室：達文西大樓U627 / A205

校內分機：2627 / 1123

E-mail: bear@tajen.edu.tw

ORCID: https://orcid.org/0000-0003-4674-3363

cool現職

  • 大仁科技大學 藥學系(含碩士班)，助理教授
  • 大仁科技大學 秘書室-校務研究與永續發展辦公室，主任。

smiley學歷

  • 高雄醫學大學，天然藥物研究所，藥學博士

indecision經歷

  • 大仁科技大學，藥學系，助理教授。
  • 博士後研究員，高雄醫學大學天然藥物研究所，2016-2023。
  • 移地研究交換學者，匈牙利賽德格大學藥學院生藥及藥化研究所，2019。

cool專長領域

  • 植物新藥前端開發、天然物暨保健食品開發。
  • 超臨界流體萃取、儀分、光譜、藥分。

enlightened成員

  • 中華天然藥物學會，永久會員。
  • 中華天然藥物學會，學術小組成員，2023。

yes榮譽

  • 優秀天然藥物學術論文獎 – 年輕學者獎，第37屆天然藥物研討會暨李國雄院士紀念會-道法自然，2022。

surpriseJournal Papers

  1. Hao-Chun Hu, Szu-Yin Yu, Yi-Hong Tsai, Pei-Wen Hsieh, Hui-Chun Wang, Yan-Ning Chen, Ya-Ting Chuang, Min-Yu Lee, Hsueh-Wei Chang, Hao-Chun Hu, Yang-Chang Wu, Fang-Rong Chang, István Szatmári, Ferenc Fulop, 2024. “Synthesis of bioactive evodiamine and rutaecarpine analogues under a ball milling condition.” Org. Biomol. Chem., accepted, in press. (Impact factor = 3.2. Ranked Q2 in CHEMISTRY, ORGANIC - SCIE).
  2. Yi-Hong Tsai1, Yen Chi Loo1, Hsieh Chen, Hui-Ping Hsieh, Yen-Chang Chen, Hsueh-Er Chen, Zhi-Hu Lin, Tse-Hung Huang, I-Min Liu, Chia-Ching Liaw, Fang-Rong Chang, 2024. “Quality and production enhancement of fish mint, Houttuynia cordata Thunb., cultivated in a hydroponic planting system with designed plant growth-promoting additives.” Heliyon, accepted, in press. (Impact factor = 4.0. Ranked Q2 in MULTIDISCIPLINARY SCIENCES - SCIE). 第一作者論文。
  3. Ya-Ting Chuang, Ching-Yu Yen, Jen-Yang Tang, Fang-Rong Chang, Yi-Hong Tsai, Kuo-Chuan Wu, Tsu-Ming Chien, Hsueh-Wei Chang, 2024. “Protein phosphatase 2A modulation and connection with miRNAs and natural products.” Envir. Toxi., accepted, in press. (Impact factor = 4.5. Ranked Q1 in TOXICOLOGY - SCIE).
  4. Ya-Ting Chuang, Ching-Yu Yen, Jun-Ping Shiau, Fang-Rong Chang, Chang-Yih Duh, Ping-Jyun Sung, Kuan-Liang Chen, Yi-Hong Tsai, Jen-Yang Tang, Jiiang-Huei Jeng, Jyh-Horng Sheu, Hsueh-Wei Chang, 2023. “Demethoxymurrapanine, an indole-naphthoquinone alkaloid, inhibits the proliferation of oral cancer cells without major side effects on normal cells.” Environ. Toxicol., 39(3):1221-1234. (Impact factor = 4.5. Ranked Q1, Top 18% in TOXICOLOGY - SCIE).
  5. Jen-Yang Tang, Ya-Ting Chuang, Jun-Ping Shiau, Ching-Yu Yen, Fang-Rong Chang, Yi-Hong Tsai, Ammad Ahmad Farooqi, Hsueh-Wei Chang, 2023. “Connection between Radiation-Regulating Functions of Natural Products and miRNAs Targeting Radiomodulation and Exosome Biogenesis.” Int. J. Mol. Sci., 24(15):12449. (Impact factor = 6.208. Ranked Q1, Top 23% in BIOCHEMISTRY & MOLECULAR BIOLOGY - SCIE).
  6. Ya-Ting Chuang, Jun-Ping Shiau, Jen-Yang Tang, Ammad Ahmad Farooqi, Fang-Rong Chang, Yi-Hong Tsai, Ching-Yu Yen, Hsueh-Wei Chang*, 2023. “Connection of Cancer Exosomal LncRNAs, Sponging miRNAs, and Exosomal Processing and Their Potential Modulation by Natural Products.” Cancers, 15(8), 2215. (Impact factor = 6.675. Ranked Q1, Top 24.29% in ONCOLOGY - SCIE).
  7. Yen Chi Loo, Hao-Chun Hu, Szu-YinYu, Yi-Hong Tsai, Michal Korinek, Yang-ChangWu*, Fang-Rong Chang*, Ying-JungChen*, 2023. “Development on potential skin anti-aging agents of Cosmos caudatus Kunth via inhibition of collagenase, MMP-1 and MMP-3 activities.” Phytomedicine, 110:154643.  (Impact factor = 6.655. Ranked Q1, No.1 in INTEGRATIVE & COMPLEMENTARY MEDICINE - SCIE).
  8. Wei-Yu Fang, Wan-Hsuan Chang, Yi-Hong Tsai, Hung-Te Hsu, Feng-Rong Chang, Chih-Lung Lin, Yi-Ching Lo*, 2023. “Guilu Erxian Jiao enhances protein synthesis, glucose homeostasis, mitochondrial biogenesis and slow-twitch fibers in the skeletal muscle.” J. Food Drug Anal., 31(1), Article 8. (Impact factor = 6.157. Ranked Q1, Top 16% in PHARMACOLOGY & PHARMACY - SCIE).
  9. Wei-Yu Fang, Chih-Lung Lin, Wan-Hsuan Chang, Chih-Hsiang Chang, Yun-Cian Huang, Yi-Hong Tsai, Fang-Rong Chang, Yi-Ching Lo*, 2022. “Protective effects of a chalcone-based derivative AN07 on inflammation-associated myotube atrophy induced by lipopolysaccharide.” Int. J. Mol. Sci., 23(21):12929. (Impact factor = 6.208. Ranked Q1, Top 23% in BIOCHEMISTRY & MOLECULAR BIOLOGY - SCIE).
  10. Hao-Chun Hu, Szu-Yin Yu, Xiao-Shan Hung, Chun-Han Su, Yu-Liang Yang, Chien-Kei Wei, Yuan-Bin Cheng, Yang-Chang Wu, Chia-Hung Yen, Tsong-Long Hwang, Shu-Li Chen, István Szatmári, Attila Hunyadi, Yi-Hong Tsai*, Fang-Rong Chang*, 2022. “Composition decipherment of F. pumila var. awkeotsang and its potential on COVID-19 symptom amelioration and in silico prediction of SARS-CoV-2 interference.” J. Food Drug Anal., 30(3), Article 9. (Impact factor = 6.157. Ranked Q1, Top 16% in PHARMACOLOGY & PHARMACY - SCIE). 通訊作者論文。
  11. Wei-Kuang Lai, Yang-Chang Wu, Tai-Sheng Yeh, Chun-Ren Hsieh, Yi-Hong Tsai, Chien-Kei Wei, Chi-Ying Li, Ying-Chen Lu*, Fang-Rong Chang*, 2021. “The protoplast two-way fusions and fusant characteristics of Antrodia cinnamomea and Cordyceps militaris.” Food Sci. Hum. Wellness, 11(5), 1240-1251. (Impact factor = 8.022. Ranked Q1, Top 10% in NUTRITION & DIETETICS - SCIE).
  12. Abdel Nasser B Singab, Nada M Mostafa, Yasmin A Elkhawas, Eman Al-Sayed, Mokhtar M Bishr, Ahmed M Elissawy, Mohamed S Elnaggar, Iten M Fawzy, Osama M Salama, Yi-Hong Tsai, Fang-Rong Chang*, 2021. “Cyclodepsipeptides: isolation from endophytic fungi of Sarcophyton ehrenbergi and verification of their larvicidal activity via in-vitro and in-silico studies.” Mar. Drugs., 20(5), 331. (Impact factor = 6.085, ranked Q1, Top 16% in CHEMISTRY, MEDICINAL - SCIE).
  13. Yi-Hong Tsai, Fang-Rong Chang*, Yang Chang Wu*, 2022. “In memory of professor Kuo-Hsiung Lee (K. H. Lee).” J. Tradit. Complement. Med. 12(2), 217-218. (Impact factor = 4.221. Ranked Q2, top 27% in INTEGRATIVE & COMPLEMENTARY MEDICINE)). 第一作者論文。
  14. Chi-Jung Tai, Mohamed El-Shazly, Yi-Hsin Yang, Yi-Hong Tsai, Dezső Csupor, Judit Hohmann, Yang-Chang Wu, Tzyy-Guey Tseng, Fang-Rong Chang*, Hui-Chun Wang*, 2022. “The effectiveness of Fuzi in combination with routine heart failure treatment on chronic heart failure patients.” J. Ethnopharmacol., 289: 115040. (Impact factor = 5.195. Ranked Q1, Top 12.98% in INTEGRATIVE & COMPLEMENTARY MEDICINE - SCIE).
  15. Chiao-Chih Huang, Tzu-Ching Lin, Chiung-Hui Liu, Hao-Chun Hu, Szu-Yin Yu, Shu-Jing Wu, Ming-Hong Yen, Yi-Hong Tsai*, Fang-Rong Chang*, 2021. “Lipid metabolism and its mechanism triggered by supercritical CO2 extract of adlay (Coix lacryma-jobi var. ma-yuen (Rom. Caill.) Stapf) bran in high fat diet-induced hyperlipidemic hamsters.” Front. Pharmacol., 12:785944. (Impact factor = 5.988. Ranked Q1, Top 18% in PHARMACOLOGY & PHARMACY - SCIE). 通訊作者論文。
  16. Michal Korinek, Heba Handoussa, Yi-Hong Tsai, You-Ying Chen, Meng-Hua Chen, Zan-Wei Chiou, Yu Fang, Fang-Rong Chang, Chia-Hung Yen, Chung-Fan Hsieh, Bing-Hung Chen, Mohamed El-Shazly, Tsong-Long Hwang, 2021. “Anti-inflammatory and antimicrobial volatile oils: Fennel and cumin inhibit neutrophilic inflammation via regulating Calcium and MAPKs.” Front. Pharmacol., 12:674095. (Impact factor = 5.988. Ranked Q1, Top 18 in PHARMACOLOGY & PHARMACY - SCIE).
  17. Kartiko Arif Purnomo, Michal Korinek, Yi-Hong Tsai, Hao-Chun Hu, Yi-Hsuan Wang, Anders Backlund, Tsong-Long Hwang, Bing-Hung Chen, Shih-Wei Wang, Chin-Chung Wu, Fang-Rong Chang*, 2021. “Decoding multiple biofunctions of maca on its anti-allergic, anti-inflammatory, anti-thrombotic, and pro-angiogenic activities.” J. Agri. Food Chem., 69(40):11856-11866. (Impact factor = 5.895. Ranked Q1, Top 10% in AGRICULTURE, MULTIDISCIPLINARY - SCIE).
  18. Bernard S. Canusa, Ivan L. Lawag, Oliver B. Villaflores, Vitthal D. Wagh, Michal Korinek, Yi-Hong Tsai, Fang-Rong Chang, Ma. Alicia M. Aguinaldo*, 2021. “α-Glucosidase inhibitors from the bark extract of ethno-antidiabetic Ceriops tagal (Perr.) C.B. Rob” Philipp. J. Sci., 151 (S1): 25-60.
  19. Yi-Hong Tsai1, Hao-Chun Hu1, Yu-Che Chuang, Kuei-Hung Lai, Yu-Ming Hsu, Tsong-Long Hwang, Chih-Chan Lin, Ferenc Fülöp, Yang-Chang Wu, Szu-Yin Yu, Yu-Ting Kuo*, Fang-Rong Chang*, 2021. “Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L.” Nat. Prod. Res., 36(12):3043-3053. (Impact factor = 2.861. Ranked Q2 in CHEMISTRY, APPLIED - SCIE). 第一作者論文。
  20. Ching-Chia Chang, Chi-Ying Li, Yi-Hong Tsai, Mohamed El-Shazly, Chien-Kei Wei, Zih-Jie Yang, Shu-Li Chen, Chin-Chung Wu, Yang-Chang Wu, Fang-Rong Chang *, 2021. “Bioactive polyketides from the pathogenic fungus of Epicoccum sorghinum.” Planta, 253(6):116. (Impact factor = 4.540. Ranked Q1, Top 17% in PLANT SCIENCES - SCIE).
  21. Chi-Jung Tai, Mohamed El-Shazly, Yi-Hong Tsai, Dezső Csupor, Judit Hohmann, Yang-Chang Wu, Tzyy-Guey Tseng, Fang-Rong Chang*, Hui-Chun Wang*, 2021. “Uncovering modern clinical applications of Fuzi and Fuzi-based formulas: A nationwide descriptive study with market basket analysis.” Front. Pharmacol., 12:674095. (Impact factor = 5.988. Ranked Q1, Top 18 in PHARMACOLOGY & PHARMACY - SCIE).
  22. Tzu-Jung Yu, Yuan-Bin Cheng, Li-Ching Lin, Yi-Hong Tsai, Bo-Yi Yao, Jen-Yang Tang, Fang-Rong Chang, Chia-Hung Yen, Fu Ou-Yang, Hsueh-Wei Chang*, 2021. “Physalis peruviana-derived physapruin A (PHA) inhibits breast cancer cell proliferation and induces oxidative-stress-mediated apoptosis and DNA damage.” Antioxidants, 10(3):393. (Impact factor = 7.675. Ranked Q1, Top 6% in CHEMISTRY, MEDICINAL - SCIE).
  23. Wei-Kuang Lai, Ying-Chen Lu, Chun-Ren Hsieh, Chien-Kei Wei, Yi-Hong Tsai, Fang-Rong Chang*, You Chan*, 2021. “Developing lactic acid bacteria as an oral healthy food.” Life-Basel, 11(4): 268. (Impact factor = 3.251. Ranked Q2 in BIOLOGY - SCIE).
  24. Hao-Chun Hu, Chi-Ying Li, Yi-Hong Tsai, Dai-Yun Yang, Yang-Chang Wu, Tsong-Long Hwang, Shu-Li Chen, Ferenc Fülöp, Attila Hunyadi, Chia-Hung Yen, Yuan-Bin Cheng, Fang-Rong Chang*, 2020. “Secondary metabolites and bioactivities of Aspergillus ochraceopetaliformis isolated from Anthurium brownie.” ACS Omega, 5(33):20991-20999. (Impact factor = 4.132. Ranked Q2 in CHEMISTRY, MULTIDISCIPLINARY - SCIE).
  25. Chi-Ying Li, Ching-Chia Chang, Yi-Hong Tsai, Mohamed El-Shazly, Chin-Chung Wu, Shih-Wei Wang, Tsong-Long Hwang, Chien-Kei Wei, Judit Hohmann, Zih-Jie Yang, Yuan-Bin Cheng, Yang-Chang Wu, Fang-Rong Chang*, 2020. “Anti-inflammatory, antiplatelet aggregation, and antiangiogenesis polyketides from Epicoccum sorghinum: Toward an understating of its biological activities and potential applications.” ACS Omega, 5(19), 11092–11099. (Impact factor = 4.132. Ranked Q2 in CHEMISTRY, MULTIDISCIPLINARY - SCIE).
  26. Chih-Wen Chen, Chih-Fong Tsai, Yi-Hong Tsai, Yang-Chang Wu*, Fang-Rong Chang*, 2020. “Association rule mining for the ordered placement of traditional Chinese medicine containers: An experimental study.” Medicine, 99(18): e20090. (Impact factor = 1.817. Ranked Q3 in MEDICINE, GENERAL & INTERNAL – SCIE).
  27. Chih‐Wen Chen, Yi‐Hong Tsai, Fang‐Rong Chang, Wei‐Chao, Lin*, 2020. “Ensemble feature selection in medical datasets: Combining filter, wrapper, and embedded feature selection results.” Expert Syst., e12553. (Impact factor = 2.812. Ranked Q2, Top 34% in COMPUTER SCIENCE, THEORY & METHODS - SCIE).
  28. Yun-Chien Lai, Chi-Jung Tai1, Mohamed El-Shazly, Yu-Che Chuang, Shu-Tuan Chiang, Yi-Hong Tsai, Dezső Csupor, Judith Hohmann, Yang-Chang Wu*, Fang-Rong Chang*, 2019. “Quantification and simplified detoxification investigation on Fuzi, root of Aconitum carmichaelii.” Nat. Prod. Commun., 14(10), 1-8.
  29. Yu-Ting Tseng, Yi-Hong Tsai¸ Ferenc Fülöp, Fang‐Rong Chang, and Yi-Ching Lo*, 2019. “2-Iodo-4’-methoxychalcone attenuates methylglyoxal-induced neurotoxicity by activation of GLP-1 receptor and enhancement of neurotrophic signal, antioxidant defense and glyoxalase pathway.” Molecules, 24(12), 2249.
  30. Hung Su, Kuan-Ting Liu, Bai-Hsiun Chen, Yen-Ping Lin, Yu-Min Jiang, Yi-Hong Tsai¸ Fang-Rong Chang, Jentaie Shiea*, Chi-Wei Lee*, 2019. “Rapid identification of herbal toxins using electrospray laser desorption ionization mass spectrometry for emergency care.” J. Food Drug Anal., 27, 2, 415−427.
  31. Chi-Ying Li, I-Wen Lo, Yen-Ping Hsueh, Yu-Ming Chung, Shih-Wei Wang, Michal Korinek, Yi-Hong Tsai¸ Yuan-Bin Cheng, Tsong-Long Hwang, Clay C. C. Wang, Fang-Rong Chang, Yang-Chang Wu, 2019. “Epigenetic manipulation induces the production of coumarin-type secondary metabolite from Arthrobotrys foliicola.” Isr. J. Chem., 59(5), 432-438.
  32. Chi-Ting Hsieh, Fang-Rong Chang, Yi-Hong Tsai, Yang-Chang Wu and Tusty-Jiuan Hsieh*, 2018. “2-Bromo-4’-methoxychalcone and 2-iodo-4’-methoxychalcone prevent progression of hyperglycemia and obesity via 5’-adenosine-monophosphate-activated protein kinase in diet-induced obese mice.” Int. J. Mol. Sci., 19(9), 2763.
  33. Yi-Hong Tsai1, Chien-Kei Wei1, Michal Korinek, Pei-Hsuan Hung, Mohamed El-Shazly, Yuan-Bin Cheng, Yang-Chang Wu, Tusty-Jiuan Hsieh*, and Fang-Rong Chang*, 2017. “6-Paradol and 6-shogaol, the pungent compounds of ginger, promote glucose utilization in adipocytes and myotubes, and 6-paradol reduces blood glucose in high-fat diet mice.” Int. J. Mol. Sci., 18(1), 168. 第一作者論文。
  34. Michal Korinek, Yi-Hong Tsai, Mohamed El-Shazly, Kuei-Hung Lai, Anders Backlund, Shou-Fang Wu, Wan-Chun Lai, Tung-Ying Wu, Shu-Li Chen, Yang-Chang Wu, Yuan-Bin Cheng, Tsong-Long Hwang*, Bing-Hung Chen*, and Fang-Rong Chang*, 2017. “Anti-allergic hydroxy fatty acids from Typhonium blumei explored through ChemGPS-NP.” Front. Pharmacol., 8, 356.
  35. Santhaseelan Henciya, Prabha Seturaman, Arthur Rathinam James, Yi-Hong Tsai, Rahul Nikam, Yang-Chang Wu, Hans-Uwe Dahms, Fang-Rong Chang*, 2017. “Biopharmaceutical potentials of Prosopis spp. (Mimosaceae, Leguminosa).” J. Food Drug Anal., 25(1), 187−196.
  36. Santhaseelan Henciya, Prabha Seturaman, Arthur Rathinam James, Yi-Hong Tsai, Rahul Nikam, Yang-Chang Wu, Hans-Uwe Dahms, Fang-Rong Chang*, 2017. “Corrigendum to “Biopharmaceutical potentials of Prosopis spp. (Mimosaceae, Leguminosa)” (Journal of Food and Drug Analysis (2017) 25(1) (S1021949816301697) (10.1016/j.jfda.2016.11.001))” J. Food Drug Anal., 25(3), 748−749.
  37. Yi-Hong Tsai1, Yuan-Bin Cheng1, I-Wen Lo, Chen-Chang Haung, Yu-Chi Tsai, Ludger Beerhues, Mohamed El-Shazly, Ming-Feng Hou, Shyng-Shiou Yuan, Chin-Chung Wu, Fang-Rong Chang*, and Yang-Chang Wu*, 2015. “Pandalisines A and B, novel indolizidine alkaloids from the leaves of Pandanus utilis.” Bioorg. Med. Chem. Lett., 25, 4333–4336. 第一作者論文。
  38. Tung-Ying Wu, Ying-Chi Du, Yu-Ming Hsu, Chi-Yu Lu, Abdel Nasser B. Singab, Mohamed El-Shazly, Tsong-Long Hwang, Wan-Yu Lin, Kuei-Hung Lai, Mei-Chin Lu, Yi-Hong Tsai, Ming-Feng Hou, Tsai-Hui Du*, and Fang-Rong Chang*, 2013. “New approach to the characterization and quantification of Antrodia cinnamomea benzenoid components utilizing HPLC-PDA, qNMR and HPLC-tandem MS: Comparing the wild fruiting bodies and its artificial cultivated commercial products.” Food Res. Int., 51, 23−31.
  39. Chia-Lin Lee, Tsong-Long Hwang, Wan-Jung He, Yi-Hong Tsai, Chiao-Ting Yen, Hsin-Fu Yen, Chao-Jung Chen, Wei-Yi Chang, Yang-Chang Wu, 2013. “Anti-neutrophilic inflammatory steroidal glycosides from Solanum torvum.” Phytochemistry, 95, 315-321.
  40. Yi-Hong Tsai1, Tusty-Jiuan Hsieh, Min-Chun Liao, Ying-Chi Du, Pei-Jung Lien, Chuan-Chia Sun, Fang-Rong Chang*, and Yang-Chang Wu*, 2012. “Anti-diabetic properties of non-polar Toona sinensis Roem. extract prepared by supercritical-CO2 fluid.” Food Chem. Toxicol., 50, 779−789. 第一作者論文。
  41. Chi-Ting Hsieh, Tusty-Jiuan Hsieh, Mohamed El-Shazly, Da-Wei Chuang, Yi-Hong Tsai, Chiao-Ting Yen, Shou-Fang Wu, Yang-Chang Wu*, and Fang-Rong Chang*, 2012. “Synthesis of Chalcone Derivatives as Potential Anti-diabetic Agents.” Bioorg. Med. Chem. Lett., 22, 3912−3915.
  42. Balaji D. Barve, Yang-Chang Wu, Mohamed El-Shazly, Da-Wei Chuang, Yu-Ming Chung, Yi-Hong Tsai, Shou-Fang Wu, Michal Korinek, Ying-Chi Du, Chi-Ting Hsieh, Jeh-Jeng Wang*, and Fang-Rong Chang*, 2012. “Synthesis of carbamates by direct C–H bond activation of formamides.” Eur. J. Org. Chem., 34, 6760−6766.
  43. Tusty-Jiuan Hsieh, Pei-Chen Hsieh, Yi-Hong Tsai, Chia-Fang Wu, Chia-Chu Liu, Ming-Yen Lin, Ming-Tsang Wu*, 2012. “Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress.” Toxicol. Sci., 130(1), 17-32.
  44. I-Min Liu, Wen-Jen Yu, Shorong-Shii Liou, Thing-Fong Tzeng, Yi-Hong Tsai, Juei-Tang Cheng*, 2006. “Role of alcohol in the induction of hepatic injury by chronic consumption of medicated wine.” J. Food Drug Anal., 15, 4, Article 4.

surprise專利

  1. 發明-Extract of Toona sinensis from supercritical fluid extraction for treating diabetes and metabolic disease, the preparation method and the use thereof ，美國，US10668122B2。
  2. 發明-抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途，台灣，I492755。
  3. 發明-抗糖尿病及抗新陈代谢疾病之香椿超临界萃取物、制备方法及用途，中國，ZL201080060000.0。
  4. 發明-Composition for treating diabetes and metabolic diseases and a preparation method thereof，美國，US9085520B2。
  5. 發明-用於治療糖尿病及新陳代謝疾病的組合物及其製備方法，台灣，I417088。
  6. 發明-Multiple beneficial functions of maca as anti-allergic, anti-neutrophilic inflammatory, anti-thrombotic, and pro-angiogenic agents and use thereof，美國，US 11,771,729 B2。
  7. 發明-馬卡多種生物功能解碼 (マカ抽出物及びその用途) ，日本，JP7446003B2。
  8. 發明-馬卡多種生物功能解碼，中國，公開號：CN115477604A。
  9. 發明-馬卡多種生物功能解碼，台灣，公開號：202300165。
  10. 發明-可抗氧化、抗發炎、抗UVB、抗過敏、美白、或抗皺的洛神葵種子萃取物，台灣，TW202337482A。
  11. 發明-可抗氧化、抗发炎、抗UVB、抗过敏、美白、保湿、以及抗皱的洛神葵种子萃取物，中國，公開號：CN116019744A。
  12. 發明-Antioxidant, anti-inflammatory, anti-uvb, anti-allergic, whitening, and anti-wrinkle roselle seed extract，美國， Filing。
  13. 發明-海葡萄萃取物用於製備促進皮膚抗發炎、抗氧化及抗癌組合物之用途，台灣，I790760。
  14. 發明-海葡萄組合物用於促進皮膚抗發炎、抗氧化、減緩膠原蛋白降解流失及抗癌之用途，台灣，I837515。
  15. 發明-魚腥草水耕培養液、系統及生產之魚腥草的萃取物與製備，台灣，I838761。
  16. 新型-萃取愛玉枝條與愛玉葉之裝置，台灣，M643653。

enlightened技術轉移及授權

  1. 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途。中華民國專利I492755。專利權人：高雄醫學大學。技轉公司：慧宇應用生物科技有限公司，團隊技轉金300,000 NTD。
  2. 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途。中國專利CN102821771B。專利權人：高雄醫學大學。技轉公司：慧宇應用生物科技有限公司，團隊技轉金額1200,000 NTD。
  3. Composition for treating diabetes and metabolic diseases and a preparation method thereof. 中華民國專利I417088, 美國專利US9085520B2。專利權人：高雄醫學大學。技轉公司：合一生技股份有限公司，合約金額30,000,000 (in milestone)。
  4. 馬卡多種生物功能解碼。美國專利US 11771729 B2、日本專利JP7446003B2、台灣、中國專利申請中。專利權人：高雄醫學大學。技轉公司：鈞禾生物科技股份有限公司。技轉金額：2,000,000。
  5. 鋅甘飲。專利權人：高雄醫學大學。技轉公司：喬本生醫股份有限公司。技轉金額：1,000,000。
  6. 活力亞補芝麻素牛樟飲。專利權人：高雄醫學大學。技轉公司：喬本生醫股份有限公司。技轉金額：1,000,000。