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Cheng-Dean Shih

Name / Position

 Cheng-Dean Shih, Ph.D./ Professor

 

Office Address

 U931, Department of Pharmacy and Master Program, Tajen University,20 Weishin Road,Yanpu Township,Pingtung County 90741, Taiwan, R.O.C.

Tel: +886-8-762-4002 ext.2931

Fax: +886-8-762-4002 ext.5121

E-mail: cdshih@tajen.edu.tw

 

Fax: 08-7624002 # 5121

 

Education

Ph.D. in Institute of Physiology (National Yang-Ming U., 1996)

M.S. in Institute of Pharmacology (National Yang-Ming U., 1992)

 

Professional Affiliation

The Chinese Physiological Society

Chinese Pharmacological Society

Neuroscience Society, R.O.C.

 

Experience
  • Associate Professor, Department of Pharmacy and Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung County, Taiwan, R.O.C.(1990-2009)
  • Professional Teacher, Continuing Education Program of Pharmacists, Kaohsiung, Taiwan, R.O.C.(2006-2007)
  • Group Leader, Office of Academic Affairs, Tajen Institute of Technology, Pingtung County, Taiwan, R.O.C.(1999-2001)
  • Pharmacist, Community Pharmacy, Kaohsiung, Taiwan, R.O.C.(1996-1997)
  • Research Assistant, Institute of Microbiology and Immunology, National Yang-Ming Medical College, Taipei, Taiwan, R.O.C.(1989-1990)
  • Pharmacist, Watsons Pharmacy, Taipei, Taiwan, R.O.C.(1993-1994)
  • Teaching Assistant, Institute of Pharmacology, National Yang-Ming Medical College, Taipei, Taiwan, R.O.C.(1990-1992)
  • Teaching Assistant, Institute of Physiology, National Yang-Ming U., Taipei, Taiwan, R.O.C.(1992-1994)

 

Expertise
  • Physiology, Neuropharmacology and Neuroscience.
  • Neuroanatomical tract tracing techniques and immunohistochemical staining.
  • Utilizing antisense oligonucleotide selectively block neuronal gene expression in the brain.
  • Microinjection of chemicals into specific the brain area.
  • Evaluation of systemic arterial pressure, heart rate, sympathetic vasomotor tone and baroreceptor reflex response.
  • Physiological and pharmacological approach to central cardiovascular regulatory mechanisms.
  • Explore social pharmacy issues such as drug safety, medication knowledge and medication adherence behaviors, etc.

 

Courses Offering

Physiology, Anatomy and Pathology

 

 

Publications
  1. Lin, C.-Y., C.-H. Chang and C.D. Shih.* (2019) A study on medication adherence of elderly in Pingtung city. Journal of Taiwan Pharmacy, 35, 115-120.
  2. Len, W.-B., M.-J. Shieh, C. Yen and C.D. Shih.* (2017) Effect of dietary habits on body mass index (BMI) of pharmacy students. Tajen Journal, 51, 25-40.
  3. Wu, K.L.H., C.-W. Wu, Y.-L. Tain, Y.-M. Chao, C.-Y. Hung, P.-C. Tsai, W.-S Wang and C.D. Shih.* (2017) Effects of high fructose intake on the development of hypertension in the spontaneously hypertensive rats: the role of AT1R/gp91PHOX signaling in the rostral ventrolateral medulla. Journal of Nutritional Biochemistry, 41, 73–83. (SCI)
  4. Chen C.-H., C.-W. Wu, C.D. Shih, W.-H. Lien, S.-L. Huang and C.-C. Huang. (2016) Attenuation of isoflurane preconditioning-induced acute cardioprotection in hypertensive hypertrophied hearts. Journal of Cardiothoracic and Vascular Anesthesia, 30, 1317-1323. (SCI)
  5. Weng, C.-Y., C.-J. Chan, H.-C. Shih and C.D. Shih.* (2016) A survey study of the medication knowledge in Yunlin and Chiayi area. Tajen Journal, 48, 17-31.
  6. Wang, S.-Y., J.-J. Lou, H.-C. Wu and C.D. Shih.* (2015) The study on medication concept in Pingtung city. Journal of Taiwan Pharmacy, 31, 132-137.
  7. Shih, C.D.* (2014) 紅景天根部水萃取物對離體動脈平滑肌細胞之抗動脈硬化作用研究。2014 Research & Development Bulletin, 19.
  8. Lu, K.-H. and C.D. Shih.* (2014) The study on factors associated with medication adherence behaviors of elderly in remote districts. Journal of Taiwan Pharmacy, 30, 149-155.
  9. Lee C.-I., C.D. Shih*, C.-L. Lee, S.-L. Kuo, S.-C. Jheng and J.-J. Wang. (2013) Effect of red mold rice on blood coagulation and anticoagulation factors in a rat model of hyperlipidemia. Journal of Functional Foods, 5, 1956-1965. (SCI)
  10. Wu, K.L.H., C.-H. Chen and C.D. Shih.* (2012) Nontranscriptional activation of PI3K/Akt signaling mediates hypotensive effect following activation of estrogen receptor beta in the rostral ventrolateral medulla of rats. Journal of Biomedical Science, 19, 76 doi: 10.1186/1423-0127-19-76. (SCI)
  11. Chiou, G.-H., D.-E. Shieh and C.D. Shih.* (2012) Effect of aqueous extract of Rhodiola crenulata radix on blood anticoagulation and c-jun N-terminal kinase in the balloon-injured rat carotid artery. The Bulletin of Society of Pharmacognosy ROC, 20, 64-65.
  12. Shih, C.D.* (2011) 紅景天根部萃取物對血壓調節之保健功能開發。農業生技產業季刊, 27, 47-53.
  13. Wang J.-J., H.-Y. Wang and C.D. Shih.* (2010) Autonomic nervous system and nitric oxide in antihypertensive and cardiac inhibitory effects induced by red mold rice in the spontaneously hypertensive rats. Journal of Agricultural and Food Chemistry, 58, 7940-7948. (SCI)
  14. Shih, C.D*., (2009) Activation of estrogen receptor beta-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats. Journal of Biomedical Science, 16, 60 doi:10.1186/1423-0127-16-60. (SCI)
  15. Shih, C.D*., (2009) Activation of nitric oxide/cGMP/PKG signaling cascade mediates antihypertensive effects of Muntingia calabura in anesthetized spontaneously hypertensive rats. American Journal of Chinese Medicine, 37, 1045-1058. (SCI)

Presentations

AT INTERNATIONAL CONFERENCES

  1. Yu, C.-J. and C.D. Shih.* (2018) The effect of drug purchasing behavior of people on medication adherence in Yunlin County: An example of a community pharmacy in Huwei Township. Presented at the 2018 Forbidden City International Pharmacists Forum, Beijing, China.
  2. Huang, C.-C., M.-C. Shieh and C.D. Shih.* (2017) A survey study on the characteristics of community pharmacy for pharmacy interns of Tajen University in Taiwan. Presented at the Seoul 2017 International Pharmaceutical Federation (FIP) World Congress, Seoul, South Korea.
  3. Shih, C.D.* and Y.-H. Ho. (2009) Inducible NOS-derived NO mediates ERβ-dependent vasodepression in rostral ventrolateral medulla. Presented at the Physiology Symposium 2009-Physiology from protein structure to function, Department of Physiology, The University of Hong Kong, Hong Kong.

 

AT NATIONAL CONFERENCES

  1. Chen, C.-H., J.-F. Hwang and C.D. Shih.* (2019) Development of probiotic enteric formula. Presented at the 34th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 23-24}
  2. Shieh, D.-E., Y. Li., Y.-J. Chen and C.D. Shih.* (2019) Study on the hypoglycemia and anti-inflammatory effects of Cyclocarya paliurus extract. Presented at the 34th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 23-24}
  3. Huang, X.-Y., Y.-R. Chen and C.D. Shih.* (2018) Effect of Fg Bβ15-42 peptide on secretion of nitric oxide in the endothelial cell. 第45屆國軍軍醫學術研討會, Taipei, Taiwan, R.O.C. {November 23}
  4. Wang, Y.-W., L.-Z. Qiu., Y.-H. Sie., S.-W. Lin., J.-S. Wu and C.D. Shih.* (2018) The drug dispensing near-miss and error incidents analyzed by using NCC MERP: A regional teaching hospital as an example. Presented at 2018 Annual Conference of Taiwan Society of Health-System Pharmacists, Kaohsiung, Taiwan, R.O.C. {November 4}
  5. Hu, M.-Y., Y.-J. Guo., S.-F. Syu., J.-S. Chen and C.D. Shih.* (2018) Satisfaction analysis of the course map of the Department of Pharmacy, Tajen University-The freshman, sophomore and junior as an example. Presented at 2018 Annual Conference of the Pharmaceutical Society of Taiwan, Kaohsiung, Taiwan, R.O.C. {October 6}
  6. Tsai, M.-C., L.-C. Chen and C.D. Shih. (2018) Development of cloud service and mobile application for drug-herb interaction query system. 長照機構藥事照護e化實務學術研討會, Kaohsiung, Taiwan, R.O.C. {May 27}
  7. Lai, L.-S., L.-C. Chen and C.D. Shih. (2018) To build the search query system for drug interaction that through cloud service and mobile application. 長照機構藥事照護e化實務學術研討會, Kaohsiung, Taiwan, R.O.C. {May 27}
  8. Shi, C.-N., L.-C. Chen and C.D. Shih. (2018) Development of drug information and appearance identification query system. 長照機構藥事照護e化實務學術研討會, Kaohsiung, Taiwan, R.O.C. {May 27}
  9. Yen, C. and C.D. Shih.* (2018) A study of dietary habits on the body mass indexes of college students-pharmacy students of Tajen University. Presented at the 33th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 25-26}
  10. Shih, C.D.* and K.-H. Lu. (2018) The influence of medication behavior on medication adherence of elderly in remote districts. Presented at the First Joint Conference of Pharmaceutical Science, Tainan, Taiwan, R.O.C. {January 13-14}
  11. Chen, H.-C. and C.D. Shih.* (2018) The study on the use of non-prescription medicines for consumers of community pharmacy in Changhua County. Presented at the First Joint Conference of Pharmaceutical Science, Tainan, Taiwan, R.O.C. {January 13-14}
  12. Chou, F.-C. and C.D. Shih.* (2018) The study of medication behavior on medication adherence in Yunlin County—Huwei Township, a community pharmacy as an example. Presented at the First Joint Conference of Pharmaceutical Science, Tainan, Taiwan, R.O.C. {January 13-14}
  13. Huang, C.-C. and C.D. Shih.* (2018) The study of pharmacy interns on internship satisfaction of community pharmacy and its influencing factors—Pharmacy students of Tajen University. Presented at the First Joint Conference of Pharmaceutical Science, Tainan, Taiwan, R.O.C. {January 13-14}
  14. Chang, H.-Y., S.-I. Hong and C.D. Shih.* (2017) Portable multifunctional pill-box with chopsticks. Presented at the 32th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 25-26}
  15. Yen, Y., C.-J. Mao., S.-J. Lin., Y.-P. Lee and C.D. Shih.* (2016) A survey study on medication cognition of elderly in long-term care facilities of Kaohsiung and Pingtung city. Presented at the 31th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 26-27}
  16. Lin, C.-Y., C.-H. Chang and C.D. Shih.* (2015) A survey study on medication adherence behaviors of elderly in district hospitals of Pingtung city. Presented at the 7th Asian Association of Schools of Pharmacy Conference, Taipei, Taiwan, R.O.C. {October 30-November 1}
  17. Weng, C.-Y., C.-J. Chan., H.-C. Shih and C.D. Shih.* (2015) A survey study of medication knowledge in Yunlin and Chiayi area. Presented at the 30th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 21-22}
  18. Wang, S.-Y., J.-J. Lou, H.-C. Wu and C.D. Shih.* (2014) Evaluation of medication concept in Pingtung train station. Presented at 2014 Annual Conference of the Pharmaceutical Society of Taiwan, Kaohsiung, Taiwan, R.O.C. {December 13}
  19. Jhan, J.-R., Y.-F. Chiu, I.-P. Hiseh, Z.-Y. Lai and C.D. Shih.* (2014) Nitric oxide and autonomic nervous system mediates antihypertensive effects of the fibrin-derived Fg Bβ15-42 peptide in the hypertensive rats. Presented at the 29th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 15-16}
  20. Jhan, J.-R., H.-W. Huang, N.-H. Wang and C.D. Shih.* (2013) Functional study of the fibrin-derived Fg Bβ15-42 peptide on blood pressure regulation. Presented at 2013 Annual Conference of the Pharmaceutical Society of Taiwan, Taipei, Taiwan, R.O.C. {December 14}
  21. Lu, K.-H. and C.D. Shih.* (2013) Medication behavior and its influencing factors of the elderly in remote districts: study on the Jiasian and Liouguei districts, Kaohsiung city. Presented at the 28th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 23-24}
  22. Lee, K.-H., D.-H. Kuo, C.D. Shih and F.-L. Lin. (2013) Study the activity of quercetin on porcine coronary arteries. Presented at 2013 TPST Medicinal Chemistry Symposium, Pingtung, Taiwan, R.O.C. {January 22-24}
  23. Lu, K.-H. and C.D. Shih.* (2012) Discussion of the remote areas Elderly medication behavior and its influencing factors. Presented at 2012 Annual Meeting of the Pharmaceutical Society of Taiwan, Taichung, Taiwan, R.O.C. {November 25}
  24. Lee, M.-J., D.-H. Kuo, C.D. Shih and F.-L. Lin. (2012) Study the activity of Flos sophorae on porcine coronary arteries. Presented at 2012 Annual Meeting of the Pharmaceutical Society of Taiwan, Taichung, Taiwan, R.O.C. {November 25}
  25. Chiou, G.-H., D.-E. Shieh and C.D. Shih.* (2012) Effect of aqueous extract of Rhodiola crenulata radix on blood anticoagulation and c-jun N-terminal kinase in the balloon-injured rat carotid artery. Presented at 2012 Annual Meeting of Society of Pharmacognosy ROC, Kaohsiung, Taiwan, R.O.C. {April 29}
  26. Chiou, G.-H., D.-E. Shieh and C.D. Shih.* (2012) Effect of aqueous extract of Rhodiola crenulata radix on blood coagulation and extracellular signal-regulated kinase in balloon-injured rat carotid artery. Presented at the 27th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 17-18}
  27. Tsai, S.-J., S.-P. Wu, C.D. Shih, S.-J. Yiin and C.-L. Chern. (2012) Fg Bβ15-42, an inhibitor of Rho kinase, up-regulates endothelial nitric oxide synthase expression and reduces blood pressure in spontaneous hypertensive rats. Presented at the Twentieth Symposium on Recent Advances in Cellular and Molecular Biology, Kaohsiung, Taiwan, R.O.C. {February 07-09}
  28. Chiou, G.-H., D.-E. Shieh and C.D. Shih.* (2011) Effect of aqueous extract of Rhodiola crenulata radix on oxidative stress and anticlotting factors in lard-treated rats. Presented at 2011 Annual Meeting of the Pharmaceutical Society of Taiwan, Pingtung, Taiwan, R.O.C. {December 03}
  29. Shieh, D.-E., G.-H. Chiou and C.D. Shih.* (2011) Effect of aqueous extract of Rhodiola crenulata radix on blood lipid and blood coagulation in lard-treated rats. Presented at the Global Chinese Health (Functional) Food Symposium 2011, Taipei, Taiwan, R.O.C. {November 20-21}
  30. Chun, H.-L. and C.D. Shih.* (2011) NADPH-dependent superoxide production in the rostral ventrolateral medulla contributes to the ovariectomy-induced hypertension in female hypertensive rats. Presented at the 26th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 19-20}
  31. Chun, H.-L. and C.D. Shih.* (2010) Activation of NADPH oxidase in the RVLM mediates ovariectomy-induced hypertension in female SHR rats. Presented at the 2010 Annual Meeting of the Pharmaceutical Society of Taiwan, Taipei, Taiwan, R.O.C. {December 11}
  32. Wu Y.-J., D.-H. Kuo and C.D. Shih.* (2010) Activation of potassium channels mediates antihypertensive and vasorelaxant effects of the essential oil of Cymbopogon citratus and its main constituent, citral. Presented at the 25th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C. {March 27-28}
  33. Wu Y.-J., D.-H. Kuo and C.D. Shih.* (2009) Cardiovascular effects of the essential oil of Cymbopogon citratus and its main constituent, citral, in normotensive and spontaneously hypertensive rats. Presented at the 2009 Annual Meeting of the Pharmaceutical Society of Taiwan, Taipei, Taiwan, R.O.C. {November 28}
  34. Chen W.-J and C.D. Shih.* (2009) The antihypertensive effects of curcumin in spontaneously hypertensive rats. Presented at the 2009 Annual Meeting of the Pharmaceutical Society of Taiwan, Taipei, Taiwan, R.O.C. {November 28}
  35. Wang J.-J., C.D. Shih, S.-C Jheng, and C.-L. Lee. (2009) Effect of red mold rice on the blood anticoagulation factors and the carotid artery balloon injury in rats. Presented at the 47th Annual Meeting of the Agricultural Chemical Society of Taiwan, Taipei, Taiwan, R.O.C.
  36. Hwang J.-F., G.-N. Chang, S.-C. Jheng, C.D. Shih and J.-J. Wang. (2009) Effect of extract from Taiwanese Angelica grown in Hualien on blood coagulation and blood anticoagulation factors. Presented at the 24th Symposium on Natural Products, Kaohsiung, Taiwan, R.O.C.
  37. Shih, C.D.* and L.-L. Wang. (2009) Nontranscriptional activation of the estrogen receptor β-dependent nitrergic neurotransmission and PI3K/Akt pathway in the hypotensive effects of estrogen in the rostral ventrolateral medulla of rats. Presented at the 24th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, R.O.C.

Personal Website
  1. The Medical Teaching Web
  2. Message Board

 

 

Patents

Inventors: Cheng-Dean Shih, Min-Fu Kuo, Chun-Yi Tseng, Shih-Kang Wang and Tso-An Yen “Medicine Cup Structure”, Utility Model No.M514848, ROC patent 2016-01-01~2025-06-17

 

Books
  1. Human Physiology, Fourth Edition, New Wun Ching Developmental Publishing Co., Ltd., September 2015 published (ISBN: 978-986-430-086-0)
  2. Human Physiology, Third Edition, New Wun Ching Developmental Publishing Co., Ltd., September 2013 published (ISBN: 978-986-236-821-0)
  3. Human Physiology, Second Edition, New Wun Ching Developmental Publishing Co., Ltd., May 2012 published (ISBN: 978-986-236-640-0)
  4. Human Physiology, New Wun Ching Developmental Publishing Co., Ltd., August 2011 published (ISBN: 978-986-236-436-9)

 

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