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鄭凱駿副教授

Journal│Conference│Book

鄭凱駿

鄭凱駿副教授       辦公室：U417     分機： 2417       

    

 學歷：

  日本鹿児島大學醫齒綜合研究所身心內科學-醫學博士

現職：
大仁科技大學/藥學系/副教授，2021/01 – NOW

經歷：

  1. 鹿児島大學大學漢方藥理學講座 特任准教授(108年3月至109年1月)
  2. 鹿児島大學大學院醫齒學綜合研究科身心內科學 特任講師(104年4月至108年2月)
  3. 鹿児島大學大學院醫齒學綜合研究科身心內科學 特任助教(102年7月至104年3月)

Email：  kc-cheng@tajen.edu.tw  

專長：漢方藥物，腦腸肽，攝食障礙、代謝疾病、行為科學。
 

 

 Journal Papers

  1. Kuo FY,Cheng KC.,Li,YX.Cheng,J.T.Oral glucose tolerance test in diabetes,the old method revisited.World J Diabetes 12(6):786-793.2021
  2. Cheng KC,Li YX,Shieh PC,Cheng JT,Hsu CC.Liraglutide activates glucagon-like peptide 1 receptor to attenuate hyperglycemia through endogenous beta-endorphin in diabetic rats.Pharmaceuticals.,13:407-417,2020.
  3. Yagi T,Ataka K,Cheng KC,Suzuki H,Ogata K,Yoshizaki Y,Takamine K,Kato I,Miyawaki S,Inui A,Asakawa A:Red rice koji extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models.Food Nutr Res.,64:4226-4235,2020.
  4. Kuo FY, Cheng KC, Li Y, Cheng JT, Tsai CC: Promotion of Adropin Expression by Hyperglycemia Is Associated with STAT3 Activation in Diabetic Rats. Diabetes Metab Syndr Obes., 13:2269-2277. 2020.
  5. Chen W, Li Y, Hsu CT, Niu CS, Pen WH, Cheng KC, Niu HS: Connective tissue growth factor in hepatocytes is elevated by carbon tetrachloride via STAT3 activation. Mol Med Rep., 21: 1390-1398. 2020.
  6. Suzuki H, Ataka K, Asakawa A, Cheng KC, Ushikai M, Iwai H, Yagi T, Arai T, Yahiro K, Yamamoto K, Yokoyama Y, Kojima M, Yada T, Hirayama T, Nakamura N, Inui A: Helicobacter pylori Vacuolating Cytotoxin A causes anorexia and anxiety via hypothalamic Urocortin 1 in Mice. Sci Rep., 9:6011. 2019
  7. Cheng KC, Cheng WT, Kuo FY, Chen ZC, Li YX, Cheng JT: TGR5 activation ameliorates hyperglycemia-induced cardiac hypertrophy in H9c2 cells. Sci Rep., 9: 3633. 2019.
  8. Kairupan TS, Cheng KC, Asakawa A, Amitani H, Yagi T, Ataka K, Rokot NT, Kapantow NH, Kato I, Inui A: Rubiscolin-6 activates opioid receptors to enhance glucose uptake in skeletal muscle. Journal of Food and Drug Analysis., 27: 266-274. 2019.
  9.  Cheng KC, Li Y, Cheng WT, Chen ZC, Cheng JT, Tsai CC: Ubiquitin-protein ligase E3a(UBE 3A) as a new biomarker of cardiac hypertrophy in cell models. Journal of Food and Drug Analysis., 27: 355-364. 2019.
  10. Cheng KC, Li Y, Chang WT, Kuo FY, Chen ZC, Cheng JT: Telmisartan is effective to ameliorate metabolic syndrome in rat model - a preclinical report. Diabetes Metab Syndr Obes., 11: 901-911. 2018.
  11. Cheng KC, Cheng WT, Li Y, Cheng YZ, Cheng JT, Cheng ZC: GW0742 activates peroxisome proliferator-activated receptor δ to reduce free radicals and alleviate cardiac hypertrophy induced by hyperglycemia in cultured H9c2 cells. J Cell Biochem., 119: 9532-9542. 2018.
  12. Kuo SC, Li Y, Cheng YZ, Lee WJ, Cheng JT, Cheng KC: Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells. Mol Med Rep., 18: 4700-4708. 2018.
  13. Chao PC, Li Y, Chang CH, Shieh JP, Cheng JT, Cheng KC: Investigation of insulin resistance in the popularly used four rat models of type-2 diabetes. Biomed Pharmacother., 101: 155-161. 2018.
  14.  Kuo SC, Li Y, Cheng KC, Niu CS, Cheng JT, Niu HS: Investigation of the pronounced erythropoietin-induced reduction in hyperglycemia in type 1-like diabetic rats. Endocr J., 65: 181-191. 2018.
  15.  Kuo SC, Li Y, Cheng KC, Niu CS, Cheng JT, Niu HS: Increase in renal erythropoietin receptors in diabetic rats is mainly mediated by hyperglycemia associated with the STAT3/GATA-1 signaling pathway. Biomed Pharmacother., 96: 1094-1102. 2017
  16.  Li Y, Cheng KC, Liu KF, Peng WH, Cheng JT, Niu HS: Telmisartan activates PPARδ to improve symptoms of unpredictable chronic mild stress-induced depression in mice. Sci Rep., 7: 14021. 2017.
  17. Wang LY, Cheng KC, Li Y, Niu CS, Cheng JT, Niu HS: Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats. Biomed Pharmacother., 95: 599-604. 2017.
  18.  Lo SH, Li Y, Cheng KC, Niu CS, Cheng JT, Niu HS: Ursolic acid activates the TGR5 receptor to enhance GLP-1 secretion in type 1-like diabetic rats. Naunyn Schmiedebergs Arch Pharmacol., 390: 1097-1104. 2017.
  19. Wang LY, Cheng KC, Li Y, Niu CS, Cheng JT, Niu HS: The dietary furocoumarin imperatorin increases plasma GLP-1 levels in type 1-like diabetic rats. Nutrients., 9: 1192-1205. 2017.
  20. Liu KF, Li Y, Cheng KC, Hsu CC, Cheng JT, Peng WH: Changes in PPARδ expression in a rat model of stress-induced depression. Clin Exp Pharmacol Physiol., 44: 664-670. 2017.
  21.  Li Y, Cheng KC, Niu CS, Lo SH, Cheng JT, Niu HS: Investigation of triamterene as an inhibitor of the TGR5 receptor: identification in cells and animals. Drug Des Devel Ther., 11: 1127-1134. 2017.
  22. Lo SH, Cheng KC, Li YX, Chang CH, Cheng JT, Lee KS: Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay. Drug Des Devel Ther., 10: 2669-2676. 2016.
  23. Runtuwene J, Cheng KC, Asakawa A, Amitani H, Amitani M, Morinaga A, Takimoto Y, Kairupan BH, Inui A: Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4. Drug Des Devel Ther., 10: 2193-2202. 2016.
  24. Li Y, Cheng KC, Asakawa A, Amitani H, Takimoto Y, Runtuwene J, Inui A: Activation of imidazoline-I3 receptors ameliorates pancreatic damage. Clin Exp Pharmacol Physiol., 42: 964-971. 2015.
  25. Amitani M, Cheng KC, Asakawa A, Amitani H, Kairupan TS, Sameshima N, Shimizu T, Hashiguchi T, Inui A: Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors. PeerJ., 3: e1105. 2015.
  26. Runtuwene J, Amitani H, Amitani M, Asakawa A, Cheng KC, Inui A: Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. Peer J., 3: e859. 2015.
  27. Yoshizaki Y, Kawasaki C, Cheng KC, Ushikai M, Amitani H, Asakawa A, Okutsu K, Sameshima Y, Takamine K, Inui A: Rice koji reduced body weight gain, fat accumulation, and blood glucose level in high-fat diet-induced obese mice. Peer J., 2: e540. 2014.
  28. Cheng KC, Asakawa A, Li YX, Chung HH, Amitani H, Ueki T, Cheng JT, Inui A: Silymarin induces insulin resistance through an increase of phosphatase and tensin homolog in wistar rats. PLoS One., 9: e84550. 2014.
  29. Li JB, Nishida M, Kaimoto K, Asakawa A, Chaolu H, Cheng KC, Li YX, Terashi M, Koyama KI, Amitani H, Sakoguchi T, Ushikai M, Ikeda S, Aoyama K, Horiuchi M, Li JZ, Inui A: Effects of aging on the plasma levels of nesfatin-1 and adiponectin. Biomed Rep., 2: 152-156. 2014.
  30. Li YX, Cheng KC, Asakawa A, Kato I, Sato Y, Amitani H, Kawamura N, Cheng JT, Inui A: Role of musclin in the pathogenesis of hypertension in rat. PLoS One., 8: e72004. 2013.
  31. Mar GY, Ku PM, Chen LJ, Cheng KC, Li YX, Cheng JT: Increase in cardiac M2-muscarinic receptor expression is regulated by GATA binding protein 4 (GATA-4) in streptozotocin-induced diabetic rats. Int J Cardiol., 167: 436-441. 2013.
  32.  Amitani H, Asakawa A, Ogiso K, Nakahara T, Ushikai M, Haruta I, Koyama K, Amitani M, Cheng KC, Inui A: The role of adiponectin multimers in anorexia nervosa. Nutrition., 29: 203-206. 2013.
  33. Koyama KI, Asakawa A, Nakahara T, Amitani H, Amitani M, Saito M, Taruno Y, Zoshiki T, Cheng KC, Yasuhara D, Inui A: Intelligence quotient and cognitive functions in severe restricting-type anorexia nervosa before and after weight gain. Nutrition., 28: 1132-1136. 2012.
 

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Conference Papers

1.  Amitani M, Amitani H, Cheng KC, Kairupan TS, Sameshima N, Shimoshikiryo I, Mizuma K, Rokot NT, Nerome Y, Owaki T, Asakawa A, Inui A: The role of ghrelin and ghrelin signaling in aging. Int J Mol Sci., 18: 1511-1538. 2017.

2.  Rokot NT, Kairupan TS, Cheng KC, Runtuwene J, Kapantow NH, Amitani M, Morinaga A, Amitani H, Asakawa A, Inui A: A role of ginseng and its constituents in the treatment of central nervous system disorders. Evid Based Complement Alternat Med., 2614742. 2016.

3.  Kairupan TS, Amitani H, Cheng KC, Runtuwene J, Asakawa A, Inui A: Role of gastrointestinal hormones in feeding behavior and obesity treatment. J Gastroenterol., 51: 93-103. 2015.

4.  Cheng KC, Asakawa A, Li YX, Liu IM, Amitani H, Cheng JT, Inui A: Opioid μ-receptors as new target for insulin resistance. Pharmacol Ther., 139: 334-340. 2013.

5.  Cheng KC, Li YX, Cheng JT: The use of herbal medicine in cancer-related anorexia/cachexia treatment around the world. Curr Pharm Des., 18: 4819-4826. 2012.

6.  Cheng KC, Li YX, Asakawa A, Inui A: The role of ghrelin in energy homeostasis and its potential clinical relevance. Int J Mol Med., 26: 771-778. 2010.
 

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Book

  1. Role of PPAR delta in diabetic cardiomyopathy.Diabetic Cardiomyopathy:Biochemical and Molecular Mechanisms.Springer,PP.1116-1124.2014.
  2. Treatment of diet-related disorders in adult diabetes.Handbook of Behavior,Food and Nutrition.Springer,PP.3375-3387.2011.

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